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The equilibrium between antagonistic signaling pathways determines the number of synapses in Drosophila

The number of synapses is a major determinant of behavior and many neural diseases exhibit deviations in that number. However, how signaling pathways control this number is still poorly understood. Using the Drosophila larval neuromuscular junction, we show here a PI3K-dependent pathway for synaptog...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jordán-Álvarez, Sheila, Santana, Elena, Casas-Tintó, Sergio, Acebes, Ángel, Ferrús, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593197/
https://ncbi.nlm.nih.gov/pubmed/28892511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184238
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