The Effects of Graded Levels of Calorie Restriction: XVI. Metabolomic Changes in the Cerebellum Indicate Activation of Hypothalamocerebellar Connections Driven by Hunger Responses

Calorie restriction (CR) remains the most robust intervention to extend life span and improve healthspan. Though the cerebellum is more commonly associated with motor control, it has strong links with the hypothalamus and is thought to be associated with nutritional regulation and adiposity. Using a...

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Vydáno v:J Gerontol A Biol Sci Med Sci
Hlavní autoři: Green, Cara L, Mitchell, Sharon E, Derous, Davina, García-Flores, Libia A, Wang, Yingchun, Chen, Luonan, Han, Jing-Dong J, Promislow, Daniel E L, Lusseau, David, Douglas, Alex, Speakman, John R
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011699/
https://ncbi.nlm.nih.gov/pubmed/33053185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glaa261
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