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Early-life undernutrition induces enhancer RNA remodeling in mice liver

BACKGROUND: Maternal protein restriction diet (PRD) increases the risk of metabolic dysfunction in adulthood, the mechanisms during the early life of offspring are still poorly understood. Apart from genetic factors, epigenetic mechanisms are crucial to offer phenotypic plasticity in response to env...

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Bibliografske podrobnosti
izdano v:Epigenetics Chromatin
Main Authors: Wang, Yinyu, Mao, Yiting, Zhao, Yiran, Yi, Xianfu, Ding, Guolian, Yu, Chuanjin, Sheng, Jianzhong, Liu, Xinmei, Meng, Yicong, Huang, Hefeng
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011416/
https://ncbi.nlm.nih.gov/pubmed/33789751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-021-00392-w
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