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MTSplice predicts effects of genetic variants on tissue-specific splicing
We develop the free and open-source model Multi-tissue Splicing (MTSplice) to predict the effects of genetic variants on splicing of cassette exons in 56 human tissues. MTSplice combines MMSplice, which models constitutive regulatory sequences, with a new neural network that models tissue-specific r...
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| 出版年: | Genome Biol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8011109/ https://ncbi.nlm.nih.gov/pubmed/33789710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02273-7 |
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