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Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain

BACKGROUND: Brain metastases are a common cause of disabling neurologic complications and death in patients with metastatic melanoma. Previous studies of nivolumab combined with ipilimumab in metastatic melanoma have excluded patients with untreated brain metastases. We evaluated the efficacy and sa...

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Détails bibliographiques
Publié dans:N Engl J Med
Auteurs principaux: Tawbi, Hussein A., Forsyth, Peter A., Algazi, Alain, Hamid, Omid, Stephen Hodi, F., Moschos, Stergios J., Khushalani, Nikhil I., Lewis, Karl, Lao, Christopher D., Postow, Michael A., Atkins, Michael B., Ernstoff, Marc S., Reardon, David A., Puzanov, Igor, Kudchadkar, Ragini R., Thomas, Reena P., Tarhini, Ahmad, Pavlick, Anna C., Jiang, Joel, Avila, Alexandre, Demelo, Sheena, Margolin, Kim
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011001/
https://ncbi.nlm.nih.gov/pubmed/30134131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1805453
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