Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain

BACKGROUND: Brain metastases are a common cause of disabling neurologic complications and death in patients with metastatic melanoma. Previous studies of nivolumab combined with ipilimumab in metastatic melanoma have excluded patients with untreated brain metastases. We evaluated the efficacy and sa...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Tawbi, Hussein A., Forsyth, Peter A., Algazi, Alain, Hamid, Omid, Stephen Hodi, F., Moschos, Stergios J., Khushalani, Nikhil I., Lewis, Karl, Lao, Christopher D., Postow, Michael A., Atkins, Michael B., Ernstoff, Marc S., Reardon, David A., Puzanov, Igor, Kudchadkar, Ragini R., Thomas, Reena P., Tarhini, Ahmad, Pavlick, Anna C., Jiang, Joel, Avila, Alexandre, Demelo, Sheena, Margolin, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011001/
https://ncbi.nlm.nih.gov/pubmed/30134131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1805453
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