Transcriptome and Functions of Granulocytic Myeloid-Derived Suppressor Cells Determine their Association with Disease Severity of COVID-19

COVID-19 ranges from asymptomatic in 35% of cases to severe in 20% of patients. Differences in the type and degree of inflammation appear to determine the severity of the disease. Recent reports show an increase in circulating monocytic-myeloid-derived suppressor cells (M-MDSC) in severe COVID 19, t...

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Publicado no:medRxiv
Main Authors: Dean, Matthew J., Ochoa, Juan B., Sanchez-Pino, Maria, Zabaleta, Jovanny, Garai, Jone, Del Valle, Luis, Wyczechowska, Dorota, Buckner, Lyndsey, Philbrook, Phaethon, Majumder, Rinku, Heide, Richard Vander, Dunkenberger, Logan, Thylur, Ramesh, Nossaman, Robert, Roberts, W. Mark, Chapple, Andrew, Collins, Jack, Luke, Brian, Johnson, Randall, Koul, Hari, Rees, Christopher A., Morris, Claudia R., Garcia-Diaz, Julia, Ochoa, Augusto C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010749/
https://ncbi.nlm.nih.gov/pubmed/33791717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.26.21254441
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