Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Dynamics Tracking

BACKGROUND: Little is known about the dynamics of SARS-CoV-2 antigen burden in respiratory samples in different patient populations at different stages of infection. Current rapid antigen tests cannot quantitate and track antigen dynamics with high sensitivity and specificity in respiratory samples....

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Publicado en:medRxiv
Main Authors: Chen, Hui, Li, Zhao, Feng, Sheng, Wang, Anni, Richard-Greenblatt, Melissa, Hutson, Emily, Andrianus, Stefen, Glaser, Laurel J., Rodino, Kyle G., Qian, Jianing, Jayaraman, Dinesh, Collman, Ronald G., Glascock, Abigail, Bushman, Frederic D., Lee, Jae Seung, Cherry, Sara, Fausto, Alejandra, Weiss, Susan R., Koo, Hyun, Corby, Patricia M., O’Doherty, Una, Garfall, Alfred L., Vogl, Dan T., Stadtmauer, Edward A., Wang, Ping
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010739/
https://ncbi.nlm.nih.gov/pubmed/33791710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.17.21253847
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