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Antagonism toward the intestinal microbiota and its effect on Vibrio cholerae virulence

The bacterial Type VI secretion system (T6SS) is a nano-machine that delivers toxic effector proteins into target cells killing them. Here we show that the V. cholerae T6SS attacks members of the host commensal microbiota in vivo, facilitating the pathogen’s colonization of the murine gut. This micr...

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Bibliografiske detaljer
Udgivet i:Science
Main Authors: Zhao, Wenjing, Caro, Florence, Robins, William, Mekalanos, John J.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010019/
https://ncbi.nlm.nih.gov/pubmed/29326272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aap8775
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