Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes

The nuclear localized protein deacetylase, SIRT6, has been identified as a crucial regulator of biological processes that drive aging. Among these processes, SIRT6 can promote resistance to oxidative stress conditions, but the precise mechanisms remain unclear. The objectives of this study were to e...

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Veröffentlicht in:Free Radic Biol Med
Hauptverfasser: Collins, John A., Kapustina, Maryna, Bolduc, Jesalyn A., Pike, James F.W., Diekman, Brian O., Mix, Kimberlee, Chubinskaya, Susan, Eroglu, Emrah, Michel, Thomas, Poole, Leslie B., Furdui, Cristina M., Loeser, Richard F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009856/
https://ncbi.nlm.nih.gov/pubmed/33600943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2021.01.054
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