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Sequential Conia-Ene-Type Cyclization and Negishi Coupling by Cooperative Functions of B(C(6)F(5))(3), ZnI(2), Pd(PPh(3))(4) and an Amine

We disclose a method for sequential Conia-ene-type cyclization/Negishi coupling for the union of alkynyl ketones and aryl iodides. This process is promoted through cooperative actions of Lewis acidic B(C(6)F(5))(3), ZnI(2), Pd-based complex, and a Brønsted basic amine. The three Lewis acid catalysts...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Cao, Min, Yesilcimen, Ahmet, Prasad, Soumil, Genova, Jason, Myers, Tanner, Wasa, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009530/
https://ncbi.nlm.nih.gov/pubmed/32915183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0ob01678k
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