Quantitative Shotgun Proteome Analysis by Direct Infusion

Liquid chromatography mass spectrometry (LC-MS) delivers sensitive peptide analysis for proteomics, but the methodology requires extensive analysis time, hampering throughput. Here, we demonstrate that using gas-phase peptide separation instead of LC enables fast proteome analysis. Using Direct Infu...

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Udgivet i:Nat Methods
Main Authors: Meyer, Jesse G., Niemi, Natalie M., Pagliarini, David J., Coon, Joshua J.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009190/
https://ncbi.nlm.nih.gov/pubmed/33230323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-00999-z
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