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Integrative proteomics and biochemical analyses define Ptc6p as the Saccharomyces cerevisiae pyruvate dehydrogenase phosphatase

The pyruvate dehydrogenase complex (PDC) is the primary metabolic checkpoint connecting glycolysis and mitochondrial oxidative phosphorylation and is important for maintaining cellular and organismal glucose homeostasis. Phosphorylation of the PDC E1 subunit was identified as a key inhibitory modifi...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Guo, Xiao, Niemi, Natalie M., Coon, Joshua J., Pagliarini, David J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512070/
https://ncbi.nlm.nih.gov/pubmed/28539364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.787341
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