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Host Epac1 is required for cAMP-mediated invasion by Trypanosoma cruzi
Mechanistic details of the modulation by cAMP of Trypanosoma cruzi host cell invasion remain ill-defined. Here we report that activation of host’s Epac1 stimulated invasion, whereas specific pharmacological inhibition or maneuvers that alter Epac1 subcellular localization significantly reduced invas...
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| Publicado no: | Mol Biochem Parasitol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8009093/ https://ncbi.nlm.nih.gov/pubmed/27984073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2016.10.003 |
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