Lifelong restriction of dietary branched-chain amino acids has sex-specific benefits for frailty and lifespan in mice

Protein restricted (PR) diets promote health and longevity in many species. While the precise components of a PR diet that mediate the beneficial effects to longevity have not been defined, we recently showed that many metabolic effects of PR can be attributed to reduced dietary levels of the branch...

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Veröffentlicht in:Nat Aging
Hauptverfasser: Richardson, Nicole E., Konon, Elizabeth N., Schuster, Haley S., Mitchell, Alexis T., Boyle, Colin, Rodgers, Allison C., Finke, Megan, Haider, Lexington R., Yu, Deyang, Flores, Victoria, Pak, Heidi H., Ahmad, Soha, Ahmed, Sareyah, Radcliff, Abigail, Wu, Jessica, Williams, Elizabeth M., Abdi, Lovina, Sherman, Dawn S., Hacker, Timothy, Lamming, Dudley W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009080/
https://ncbi.nlm.nih.gov/pubmed/33796866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43587-020-00006-2
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