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Transition metal-catalysed A-ring C–H activations and C(sp(2))–C(sp(2)) couplings in the 13α-oestrone series and in vitro evaluation of antiproliferative properties

Facile syntheses of 3-O-carbamoyl, -sulfamoyl, or -pivaloyl derivatives of 13α-oestrone and its 17-deoxy counterpart have been carried out. Microwave-induced, Ni-catalysed Suzuki–Miyaura couplings of the newly synthesised phenol esters with phenylboronic acid afforded 3-deoxy-3-phenyl-13α-oestrone d...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Traj, Péter, Abdolkhaliq, Ali Hazhmat, Németh, Anett, Dajcs, Sámuel Trisztán, Tömösi, Ferenc, Lanisnik-Rizner, Tea, Zupkó, István, Mernyák, Erzsébet
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008932/
https://ncbi.nlm.nih.gov/pubmed/33771084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1900165
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