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Transition metal-catalysed A-ring C–H activations and C(sp(2))–C(sp(2)) couplings in the 13α-oestrone series and in vitro evaluation of antiproliferative properties
Facile syntheses of 3-O-carbamoyl, -sulfamoyl, or -pivaloyl derivatives of 13α-oestrone and its 17-deoxy counterpart have been carried out. Microwave-induced, Ni-catalysed Suzuki–Miyaura couplings of the newly synthesised phenol esters with phenylboronic acid afforded 3-deoxy-3-phenyl-13α-oestrone d...
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| Publicado no: | J Enzyme Inhib Med Chem |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8008932/ https://ncbi.nlm.nih.gov/pubmed/33771084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1900165 |
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