Human DNA decays faster with time than viral dsDNA: an analysis on HPV16 using pathology archive samples spanning 85 years

BACKGROUND: Quality of the nucleic acids extracted from Formalin Fixed Paraffin Embedded (FFPE) samples largely depends on pre-analytic, fixation and storage conditions. We assessed the differential sensitivity of viral and human double stranded DNA (dsDNA) to degradation with storage time. METHODS:...

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Bibliografische gegevens
Gepubliceerd in:Virol J
Hoofdauteurs: Nicolás-Párraga, Sara, Torres, Montserrat, Alemany, Laia, Félix, Ana, Cruz, Eugenia, de Sanjosé, Silvia, Bosch, Francesc Xavier, Bravo, Ignacio G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008572/
https://ncbi.nlm.nih.gov/pubmed/33781303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-021-01529-9
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