Polyubiquitin and ubiquitin-like signals share common recognition sites on proteasomal subunit Rpn1

Proteasome-mediated substrate degradation is an essential process that relies on the coordinated actions of ubiquitin (Ub), shuttle proteins containing Ub-like (UBL) domains, and the proteasome. Proteinaceous substrates are tagged with polyUb and shuttle proteins, and these signals are then recogniz...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Boughton, Andrew J., Zhang, Daoning, Singh, Rajesh K., Fushman, David
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2021
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008175/
https://ncbi.nlm.nih.gov/pubmed/33617881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100450
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