Ahi1 regulates the nuclear translocation of glucocorticoid receptor to modulate stress response

Stress activates the nuclear translocation of glucocorticoid receptors (GR) to trigger gene expression. Abnormal GR levels can alter the stress responses in animals and therapeutic effects of antidepressants. Here, we reported that stress-mediated nuclear translocation of GR reduced Ahi1 in the stre...

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Pubblicato in:Transl Psychiatry
Autori principali: Wang, Bin, Xin, Ning, Qian, Xuanchen, Zhai, Lijing, Miao, Zhigang, Yang, Yong, Li, Shihua, Sun, Miao, Xu, Xingshun, Li, Xiao-Jiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007735/
https://ncbi.nlm.nih.gov/pubmed/33782379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01305-x
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