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Differential effect of glucocorticoid receptor antagonists on glucocorticoid receptor nuclear translocation and DNA binding

The effects of RU486 and S-P, a more selective glucocorticoid receptor antagonist from Schering-Plough, were investigated on glucocorticoid receptor nuclear translocation and DNA binding. In the in vitro study, AtT20 cells were treated with vehicle or with RU486, S-P or corticosterone (3–300 nM) or...

詳細記述

保存先:
書誌詳細
出版年:J Psychopharmacol
主要な著者: Spiga, Francesca, Knight, David M, Droste, Susanne K, Conway-Campbell, Becky, Kershaw, Yvonne, MacSweeney, Cliona P, Thomson, Fiona J, Craighead, Mark, Peeters, Bernard WMM, Lightman, Stafford L
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984974/
https://ncbi.nlm.nih.gov/pubmed/20093322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881109348175
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