Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagy

Influenza A virus (IAV) infection induces mitophagy, which is essential for the clearance of damaged mitochondria. Dysfunctional mitochondria can be selectively targeted by PINK1, which recruits PRKN/PARK2 and leads to subsequent mitochondrial sequestration within autophagosomes. The IAV PB1-F2 prot...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Autophagy
Main Authors: Wang, Ruifang, Zhu, Yinxing, Ren, Chenwei, Yang, Shuaike, Tian, Shan, Chen, Huanchun, Jin, Meilin, Zhou, Hongbo
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2020
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007153/
https://ncbi.nlm.nih.gov/pubmed/32013669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1725375
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