Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagy

Influenza A virus (IAV) infection induces mitophagy, which is essential for the clearance of damaged mitochondria. Dysfunctional mitochondria can be selectively targeted by PINK1, which recruits PRKN/PARK2 and leads to subsequent mitochondrial sequestration within autophagosomes. The IAV PB1-F2 prot...

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Publicado en:Autophagy
Autores principales: Wang, Ruifang, Zhu, Yinxing, Ren, Chenwei, Yang, Shuaike, Tian, Shan, Chen, Huanchun, Jin, Meilin, Zhou, Hongbo
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007153/
https://ncbi.nlm.nih.gov/pubmed/32013669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1725375
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