Cholesterol derivatives induce dephosphorylation of the histone deacetylases Rpd3/HDAC1 to upregulate autophagy

Histone deacetylases (HDACs) are important for global gene expression and contribute to numerous physiological events. Deacetylase Rpd3 in yeast and its conserved homolog HDAC1 in mammals oppositely regulate autophagy; however, how Rpd3/HDAC1 is regulated to mediate autophagy remains unclear. Here,...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Wu, Wenmei, Luo, Man, Li, Kang, Dai, Yichen, Yi, Huiyu, Zhong, Yangjin, Cao, Yang, Tettamanti, Gianluca, Tian, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007145/
https://ncbi.nlm.nih.gov/pubmed/32013726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1725376
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