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Induction of autophagy increases the proteolytic activity of reservosomes during Trypanosoma cruzi metacyclogenesis

Cruzipain, the major cysteine protease of the pathogenic protozoa Trypanosoma cruzi, is an important virulence factor that plays a key role in the parasite nutrition, differentiation and host cell infection. Cruzipain is synthesized as a zymogen, matured, and delivered to reservosomes. These organel...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Losinno, Antonella Denise, Martínez, Santiago José, Labriola, Carlos Alberto, Carrillo, Carolina, Romano, Patricia Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007142/
https://ncbi.nlm.nih.gov/pubmed/31983275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1720428
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