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Induction of autophagy increases the proteolytic activity of reservosomes during Trypanosoma cruzi metacyclogenesis

Cruzipain, the major cysteine protease of the pathogenic protozoa Trypanosoma cruzi, is an important virulence factor that plays a key role in the parasite nutrition, differentiation and host cell infection. Cruzipain is synthesized as a zymogen, matured, and delivered to reservosomes. These organel...

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Détails bibliographiques
Publié dans:Autophagy
Auteurs principaux: Losinno, Antonella Denise, Martínez, Santiago José, Labriola, Carlos Alberto, Carrillo, Carolina, Romano, Patricia Silvia
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007142/
https://ncbi.nlm.nih.gov/pubmed/31983275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1720428
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