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Histone H3K9 methylation regulates chronic stress and IL-6-induced colon epithelial permeability and visceral pain

BACKGROUND: Chronic stress is associated with activation of the HPA-axis, elevation in pro-inflammatory cytokines, decrease in intestinal epithelial cell tight junction (TJ) proteins and enhanced visceral pain. It is unknown whether epigenetic regulatory pathways play a role in chronic stress-induce...

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Bibliographische Detailangaben
Veröffentlicht in:Neurogastroenterol Motil
Hauptverfasser: Wiley, John W, Zong, Ye, Zheng, Gen, Zhu, Shengtao, Hong, Shuangsong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007084/
https://ncbi.nlm.nih.gov/pubmed/32743845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nmo.13941
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