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De Novo Design, Solution Characterization, and Crystallographic Structure of an Abiological Mn−Porphyrin-Binding Protein Capable of Stabilizing a Mn(V) Species

De novo protein design offers the opportunity to test our understanding of how metalloproteins perform difficult transformations. Attaining high-resolution structural information is critical to understanding how such designs function. There have been many successes in the design of porphyrin-binding...

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Publicat a:J Am Chem Soc
Autors principals: Mann, Samuel I., Nayak, Animesh, Gassner, George T., Therien, Michael J., DeGrado, William F.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006777/
https://ncbi.nlm.nih.gov/pubmed/33373215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c10136
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