Doxorubicin‐induced and trastuzumab‐induced cardiotoxicity in mice is not prevented by metoprolol

AIMS: Our objectives were to validate a murine model of chronic cardiotoxicity induced by Doxorubicin (Dox) and Trastuzumab (Trast) and to test the potential cardio‐protective effect of metoprolol. METHODS AND RESULTS: Male C57Bl6 mice were intraperitoneally injected during 2 weeks with Dox (24 mg/k...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ESC Heart Fail
Prif Awduron: Nicol, Martin, Sadoune, Malha, Polidano, Evelyne, Launay, Jean Marie, Samuel, Jane Lise, Azibani, Feriel, Cohen‐Solal, Alain
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2021
Pynciau:
Original Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006653/
https://ncbi.nlm.nih.gov/pubmed/33529501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ehf2.13198
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