Ebola-GP DNA Prime rAd5-GP Boost: Influence of Prime Frequency and Prime/Boost Time Interval on the Immune Response in Non-human Primates

Heterologous prime-boost immunization regimens are a common strategy for many vaccines. DNA prime rAd5-GP boost immunization has been demonstrated to protect non-human primates against a lethal challenge of Ebola virus, a pathogen that causes fatal hemorrhagic disease in humans. This protection corr...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Marcus, Hadar, Thompson, Emily, Zhou, Yan, Bailey, Michael, Donaldson, Mitzi M., Stanley, Daphne A., Asiedu, Clement, Foulds, Kathryn E., Roederer, Mario, Moliva, Juan I., Sullivan, Nancy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006325/
https://ncbi.nlm.nih.gov/pubmed/33790899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.627688
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