Prime-Boost Vaccination with rBCG/rAd35 Enhances CD8(+) Cytolytic T-Cell Responses in Lesions from Mycobacterium Tuberculosis –Infected Primates

To prevent the global spread of tuberculosis (TB) infection, a novel vaccine that triggers potent and long-lived immunity is urgently required. A plasmid-based vaccine has been developed to enhance activation of major histocompatibility complex (MHC) class I–restricted CD8+ cytolytic T cells using a...

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Autors principals: Rahman, Sayma, Magalhaes, Isabelle, Rahman, Jubayer, Ahmed, Raija K, Sizemore, Donata R, Scanga, Charles A, Weichold, Frank, Verreck, Frank, Kondova, Ivanela, Sadoff, Jerry, Thorstensson, Rigmor, Spångberg, Mats, Svensson, Mattias, Andersson, Jan, Maeurer, Markus, Brighenti, Susanna
Format: Artigo
Idioma:Inglês
Publicat: ScholarOne 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388130/
https://ncbi.nlm.nih.gov/pubmed/22396020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00222
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