Spleen Tyrosine Kinase Inhibition Ameliorates Tubular Inflammation in IgA Nephropathy

Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase involved in signal transduction in a variety of immune responses. It has been demonstrated that Syk plays a pathogenic role in orchestrating inflammatory responses and cell proliferation in human mesangial cells (HMC) in IgA nephropathy...

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Udgivet i:Front Physiol
Main Authors: Yiu, Wai Han, Chan, Kam Wa, Chan, Loretta Y. Y., Leung, Joseph C. K., Lai, Kar Neng, Tang, Sydney C. W.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006276/
https://ncbi.nlm.nih.gov/pubmed/33790807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.650888
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