Oxidative damages in tubular epithelial cells in IgA nephropathy: role of crosstalk between angiotensin II and aldosterone

BACKGROUND: Inhibition of the renin-angiotensin-aldosterone system (RAAS) slows down the progression of chronic renal diseases (CKD) including IgA nephropathy (IgAN). Herein, we studied the pathogenetic roles of aldosterone (Aldo) in IgAN. METHODS: Human mesangial cells (HMC) was activated with poly...

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Detalhes bibliográficos
Main Authors: Leung, Joseph CK, Chan, Loretta YY, Tang, Sydney CW, Lam, Man-Fai, Chow, Chui-Wa, Lim, Ai-Ing, Lai, Kar-Neng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203061/
https://ncbi.nlm.nih.gov/pubmed/21974877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-169
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