HDX-MS for Epitope Characterization of a Therapeutic ANTIBODY Candidate on the Calcium-Binding Protein Annexin-A1

Annexin-A1 (ANXA1) belongs to a class of highly homologous Ca(2+)-dependent phospholipid-binding proteins. Its structure consists of a core region composed of four homologous repeats arranged in a compact, hydrolysis-resistant structure and an N-terminal region with a Ca(2+)-dependent conformation....

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Detalhes bibliográficos
Publicado no:Antibodies (Basel)
Main Authors: Gramlich, Marius, Hays, Henry C. W., Crichton, Scott, Kaiser, Philipp D., Heine, Anne, Schneiderhan-Marra, Nicole, Rothbauer, Ulrich, Stoll, Dieter, Maier, Sandra, Zeck, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006148/
https://ncbi.nlm.nih.gov/pubmed/33808657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib10010011
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