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Conformation of the von Willebrand factor/factor VIII complex in quasi-static flow

Von Willebrand factor (VWF) is a plasma glycoprotein that circulates noncovalently bound to blood coagulation factor VIII (fVIII). VWF is a population of multimers composed of a variable number of ∼280 kDa monomers that is activated in shear flow to bind collagen and platelet glycoprotein Ibα. Elect...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Parker, Ernest T., Lollar, Pete
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005835/
https://ncbi.nlm.nih.gov/pubmed/33600794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100420
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