The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders

The widespread distribution of heteroreceptor complexes with allosteric receptor-receptor interactions in the CNS represents a novel integrative molecular mechanism in the plasma membrane of neurons and glial cells. It was proposed that they form the molecular basis for learning and short-and long-t...

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Vydáno v:Front Pharmacol
Hlavní autoři: Borroto-Escuela, Dasiel O., Wydra, Karolina, Fores-Pons, Ramon, Vasudevan, Lakshmi, Romero-Fernandez, Wilber, Frankowska, Małgorzata, Ferraro, Luca, Beggiato, Sarah, Crespo-Ramirez, Minerva, Rivera, Alicia, Rocha, Luisa L., Perez de la Mora, Miguel, Stove, Christophe, Filip, Małgorzata, Fuxe, Kjell
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005530/
https://ncbi.nlm.nih.gov/pubmed/33790790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.627032
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