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Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D(2) Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor

The interplay between the dopamine (DA) and opioid systems in the brain is known to modulate the additive effects of substances of abuse. On one hand, opioids serve mankind by their analgesic properties, which are mediated via the mu opioid receptor (MOR), a Class A G protein-coupled receptor (GPCR)...

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Publicat a:Biomolecules
Autors principals: Vasudevan, Lakshmi, Borroto-Escuela, Dasiel O., Huysentruyt, Jelle, Fuxe, Kjell, Saini, Deepak K., Stove, Christophe
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722706/
https://ncbi.nlm.nih.gov/pubmed/31416253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9080368
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