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Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D(2) Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor

The interplay between the dopamine (DA) and opioid systems in the brain is known to modulate the additive effects of substances of abuse. On one hand, opioids serve mankind by their analgesic properties, which are mediated via the mu opioid receptor (MOR), a Class A G protein-coupled receptor (GPCR)...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Vasudevan, Lakshmi, Borroto-Escuela, Dasiel O., Huysentruyt, Jelle, Fuxe, Kjell, Saini, Deepak K., Stove, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722706/
https://ncbi.nlm.nih.gov/pubmed/31416253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9080368
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