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Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D(2) Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor

The interplay between the dopamine (DA) and opioid systems in the brain is known to modulate the additive effects of substances of abuse. On one hand, opioids serve mankind by their analgesic properties, which are mediated via the mu opioid receptor (MOR), a Class A G protein-coupled receptor (GPCR)...

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Dettagli Bibliografici
Pubblicato in:Biomolecules
Autori principali: Vasudevan, Lakshmi, Borroto-Escuela, Dasiel O., Huysentruyt, Jelle, Fuxe, Kjell, Saini, Deepak K., Stove, Christophe
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722706/
https://ncbi.nlm.nih.gov/pubmed/31416253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9080368
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