FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma.

The PAX3-FOXO1 fusion protein is the key oncogenic driver in fusion positive rhabdomyosarcoma (FP-RMS), an aggressive soft tissue malignancy with a particularly poor prognosis. Identifying key downstream targets of PAX3-FOXO1 will provide new therapeutic opportunities for treatment of FP-RMS. Herein...

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Publicat a:Oncogene
Autors principals: Milewski, David, Shukla, Samriddhi, Gryder, Berkley E., Pradhan, Arun, Donovan, Johnny, Sudha, Parvathi, Vallabh, Sushmitha, Pyros, Athena, Xu, Yan, Barski, Artem, Szabo, Sara, Turpin, Brian, Pressey, Joseph G., Millay, Douglas P., Khan, Javed, Kalinichenko, Vladimir V., Kalin, Tanya V.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005492/
https://ncbi.nlm.nih.gov/pubmed/33627785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01694-9
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