FoxF1 and FoxF2 transcription factors synergistically promote Rhabdomyosarcoma carcinogenesis by repressing transcription of p21(Cip1) CDK inhibitor

The role of Forkhead Box F1 (FoxF1) transcription factor in carcinogenesis is not well characterized. Depending on tissue and histological type of cancer, FoxF1 was shown to be either oncogene or tumor suppressor. Alveolar rhabdomyosarcoma (RMS) is the most aggressive pediatric soft tissue sarcoma....

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Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Milewski, David, Pradhan, Arun, Wang, Xinjian, Cai, Yuqi, Le, Tien, Turpin, Brian, Kalinichenko, Vladimir V., Kalin, Tanya V.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243941/
https://ncbi.nlm.nih.gov/pubmed/27425595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.254
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