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A pentamethoxylated flavone from Glycosmis ovoidea promotes apoptosis through the intrinsic pathway and inhibits migration of MCF-7 breast cancer cells

The rare flavone 5,3’-dihydroxy-3,6,7,8,4’-pentamethoxyflavone (PMF) has been isolated from several plant species, and its cytotoxic activity has been reported against many types of cancer cells. In this study, PMF was purified from Glycomis ovoidea collected in Vietnam, and its antiproliferative ef...

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Publicado en:Phytother Res
Autores principales: Anaya-Eugenio, Gerardo D., Blanco Carcache, Peter J., Ninh, Tran Ngoc, Ren, Yulin, Soejarto, Djaja D., Kinghorn, A. Douglas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005457/
https://ncbi.nlm.nih.gov/pubmed/33124130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ptr.6930
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