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Transient phases of OXPHOS inhibitor resistance reveal underlying metabolic heterogeneity in single cells
Cell-to-cell heterogeneity in metabolism plays an unknown role in physiology and pharmacology. To functionally characterize cellular variability in metabolism, we treated cells with inhibitors of oxidative phosphorylation (OXPHOS) and monitored their responses with live-cell reporters for ATP, ADP/A...
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| Publicado en: | Cell Metab |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8005262/ https://ncbi.nlm.nih.gov/pubmed/33561427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2021.01.014 |
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