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Assessment of Amyloid Forming Tendency of Peptide Sequences from Amyloid Beta and Tau Proteins Using Force-Field, Semi-Empirical, and Density Functional Theory Calculations

A wide variety of neurodegenerative diseases are characterized by the accumulation of protein aggregates in intraneuronal or extraneuronal brain regions. In Alzheimer’s disease (AD), the extracellular aggregates originate from amyloid-β proteins, while the intracellular aggregates are formed from mi...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Int J Mol Sci
Main Authors: Muvva, Charuvaka, Murugan, Natarajan Arul, Subramanian, Venkatesan
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005029/
https://ncbi.nlm.nih.gov/pubmed/33806726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22063244
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