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Hereditary Spastic Paraplegia: From Genes, Cells and Networks to Novel Pathways for Drug Discovery

Hereditary spastic paraplegia (HSP) is a diverse group of Mendelian genetic disorders affecting the upper motor neurons, specifically degeneration of their distal axons in the corticospinal tract. Currently, there are 80 genes or genomic loci (genomic regions for which the causative gene has not bee...

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Detalhes bibliográficos
Publicado no:Brain Sci
Autor principal: Mackay-Sim, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004882/
https://ncbi.nlm.nih.gov/pubmed/33810178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci11030403
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