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Lysosome Function and Dysfunction in Hereditary Spastic Paraplegias

Hereditary Spastic Paraplegias (HSPs) are a genetically diverse group of inherited neurological diseases with over 80 associated gene loci. Over the last decade, research into mechanisms underlying HSPs has led to an emerging interest in lysosome dysfunction. In this review, we highlight the differe...

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Bibliographische Detailangaben
Veröffentlicht in:Brain Sci
Hauptverfasser: Edmison, Daisy, Wang, Luyu, Gowrishankar, Swetha
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911997/
https://ncbi.nlm.nih.gov/pubmed/33498913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci11020152
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