Cross-Resistance to Abiraterone and Enzalutamide in Castration Resistance Prostate Cancer Cellular Models Is Mediated by AR Transcriptional Reactivation

SIMPLE SUMMARY: Prostate cancer is the second most common cancer in males. In prostate cancer cells, androgens bind and activate the intracellular mediator called Androgen Receptor that control cell proliferation and survival. Hormone deprivation therapy is administrated to reduce androgen levels an...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Simon, Iris, Perales, Sonia, Casado-Medina, Laura, Rodríguez-Martínez, Alba, Garrido-Navas, Maria del Carmen, Puche-Sanz, Ignacio, Diaz-Mochon, Juan J., Alaminos, Clara, Lupiañez, Pablo, Lorente, Jose A., Serrano, María J., Real, Pedro J.
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004828/
https://ncbi.nlm.nih.gov/pubmed/33807106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061483
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