Microglial Cell Morphology and Phagocytic Activity Are Critically Regulated by the Neurosteroid Allopregnanolone: A Possible Role in Neuroprotection

Microglial cells are key players in neural pathogenesis and microglial function regulation appears to be pivotal in controlling neuroinflammatory/neurological diseases. Here, we investigated the effects and mechanism of action of neurosteroid allopregnanolone (ALLO) on murine microglial BV-2 cells a...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Jolivel, Valérie, Brun, Susana, Binamé, Fabien, Benyounes, Jérémie, Taleb, Omar, Bagnard, Dominique, De Sèze, Jérôme, Patte-Mensah, Christine, Mensah-Nyagan, Ayikoe-Guy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004004/
https://ncbi.nlm.nih.gov/pubmed/33801063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10030698
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