Neurosteroid 3α-Androstanediol Efficiently Counteracts Paclitaxel-Induced Peripheral Neuropathy and Painful Symptoms

Painful peripheral neuropathy belongs to major side-effects limiting cancer chemotherapy. Paclitaxel, widely used to treat several cancers, induces neurological symptoms including burning pain, allodynia, hyperalgesia and numbness. Therefore, identification of drugs that may effectively counteract p...

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Autores principales: Meyer, Laurence, Patte-Mensah, Christine, Taleb, Omar, Mensah-Nyagan, Ayikoe Guy
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829913/
https://ncbi.nlm.nih.gov/pubmed/24260511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080915
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