The Prognostic and Predictive Role of Somatic BRCA Mutations in Ovarian Cancer: Results from a Multicenter Cohort Study

Previous research involving epithelial ovarian cancer patients showed that, compared to germline BRCA (gBRCA) mutations, somatic BRCA (sBRCA) mutations present a similar positive impact with regard to overall survival (OS) and platinum and PARP (poly (ADP-ribose) polymerase) inhibitor sensitivity. N...

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Detalhes bibliográficos
Publicado no:Diagnostics (Basel)
Main Authors: Toss, Angela, Piombino, Claudia, Tenedini, Elena, Bologna, Alessandra, Gasparini, Elisa, Tarantino, Vittoria, Filieri, Maria Elisabetta, Cottafavi, Luca, Giovanardi, Filippo, Madrigali, Stefano, Civallero, Monica, Marcheselli, Luigi, Marchi, Isabella, Domati, Federica, Venturelli, Marta, Barbieri, Elena, Grandi, Giovanni, Tagliafico, Enrico, Cortesi, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8003908/
https://ncbi.nlm.nih.gov/pubmed/33801055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics11030565
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