BRCA mutation rate and characteristics of prostate tumor in breast and ovarian cancer families: analysis of 6,591 Italian pedigrees

OBJECTIVE: As prostate cancer (PrC) shows a BRCA mutation rate as high as 30%, it becomes crucial to find the optimal selection criteria for genetic testing. The primary objective of this study was to evaluate the BRCA mutation rate in families with PrC associated with breast and/or ovarian cancers;...

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Detalhes bibliográficos
Publicado no:Cancer Biol Med
Main Authors: Cortesi, Laura, Domati, Federica, Guida, Annalisa, Marchi, Isabella, Toss, Angela, Barbieri, Elena, Marcheselli, Luigi, Venturelli, Marta, Piana, Simonetta, Cirilli, Claudia, Federico, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Compuscript 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185862/
https://ncbi.nlm.nih.gov/pubmed/33710808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2020.0481
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