Cytotoxic Efficacy and Resistance Mechanism of a TRAIL and VEGFA-Peptide Fusion Protein in Colorectal Cancer Models

TNF-related apoptosis-inducing ligand (TRAIL) is a type II transmembrane protein capable of selectively inducing apoptosis in cancer cells by binding to its cognate receptors. Here, we examined the anticancer efficacy of a recently developed chimeric AD-O51.4 protein, a TRAIL fused to the VEGFA-orig...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kopczynski, Michal, Statkiewicz, Malgorzata, Cybulska, Magdalena, Kuklinska, Urszula, Unrug-Bielawska, Katarzyna, Sandowska-Markiewicz, Zuzanna, Grochowska, Aleksandra, Gajewska, Marta, Kulecka, Maria, Ostrowski, Jerzy, Mikula, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8003782/
https://ncbi.nlm.nih.gov/pubmed/33808900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22063160
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