Challenges in Stratifying the Molecular Variability of Patient-Derived Colon Tumor Xenografts

Colorectal cancer (CRC) is the second most common cancer in Europe and a leading cause of death worldwide. Patient-derived xenograft (PDX) models maintain complex intratumoral biology and heterogeneity and therefore remain the platform of choice for translational drug discovery. In this study, we im...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Cybulska, Magdalena, Olesinski, Tomasz, Goryca, Krzysztof, Paczkowska, Katarzyna, Statkiewicz, Malgorzata, Kopczynski, Michal, Grochowska, Aleksandra, Unrug-Bielawska, Katarzyna, Tyl-Bielicka, Anita, Gajewska, Marta, Mroz, Andrzej, Dabrowska, Michalina, Karczmarski, Jakub, Paziewska, Agnieszka, Zając, Leszek, Bednarczyk, Mariusz, Mikula, Michal, Ostrowski, Jerzy
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6313970/
https://ncbi.nlm.nih.gov/pubmed/30662905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2954208
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