Efficacy of Targeted Radionuclide Therapy Using [(131)I]ICF01012 in 3D Pigmented BRAF- and NRAS-Mutant Melanoma Models and In Vivo NRAS-Mutant Melanoma

SIMPLE SUMMARY: Targeted radionuclide therapy (TRT) aims to selectively deliver radioactive molecules to tumor cells. For this purpose, we deliver iodine-131 ([(131)I]) to melanoma cells by using our laboratory-developed melanin specific radiotracer, the ICF01012. Approximately 50% and 20%–30% of hu...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Akil, Hussein, Quintana, Mercedes, Raymond, Jérémy H., Billoux, Tommy, Benboubker, Valentin, Besse, Sophie, Auzeloux, Philippe, Delmas, Véronique, Petit, Valérie, Larue, Lionel, D’Incan, Michel, Degoul, Françoise, Rouanet, Jacques
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8003594/
https://ncbi.nlm.nih.gov/pubmed/33804655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061421
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